A new study shows Pfizer's heartburn pill Nexium and similar brands could be a game-changer in the market for heartburn treatment. The two drugs are used together to treat more than 1 million Americans who have heartburn, according to data from the.
The study, released this week in, found that patients taking Nexium for more than four months had a 50 percent higher chance of getting heartburn than those taking a placebo, a difference that doctors are expected to make when they decide whether to treat heartburn with Nexium.
The study was published online in theJournal of the American Medical Association.
"We want to see more patients in this population who can have a better overall outcome," said Dr. Michael J. D'Anconazio, an associate professor of medicine at Georgetown University School of Medicine and director of the research project.
The study's findings come on the heels of the's, published on Tuesday, in theNew England Journal of Medicine, and the FDA's, published on March 10.
The study was the latest in a series of, published in February on the.
Researchers examined data from over 1,400 doctors who treat heartburn for 10 years and who have been on the drug for more than four months.
Dr. Michael D'Anconazio, who is the chief investigator on the study, said that while the results showed that patients taking the drugs had a "somewhat higher" chance of getting heartburn, that's not a guarantee.
That could change for other patients, too.
"It's going to take some time for doctors to be able to make the judgment based on patient characteristics, but the number of people taking the drugs is probably going to be higher because of these factors," he said.
The drugs, including Nexium and Prilosec, are also used for the treatment of heartburn, which is a serious condition that causes painful and burning in the chest. They're known for their antacids, which help prevent heartburn from happening. However, doctors do not generally recommend taking them together.
The study was conducted by a group of researchers led by theAmerican Heart Association
Michael D'Anconazio, who is also the lead investigator on the study, said the results are based on an analysis of the data from all doctors who have treated heartburn for 10 years and have been on the drug for more than four months.
Michael D'Anconazio, who was the principal investigator for the study, said that while the findings show that patients taking Nexium and Prilosec had a 50 percent higher chance of getting heartburn, that's not necessarily a guarantee, especially in the context of the drug's antacids.
Michael D'Anconazio, who is also the lead investigator on the study, said that while the results show that patients taking the drugs had a 50 percent higher chance of getting heartburn, that's not necessarily a guarantee.
There are other factors that might influence the overall likelihood of getting heartburn, including the drugs' effect on blood pressure, which can affect how well the drug works, and the severity of the heartburn, which may make the overall result more difficult to measure.
The study's lead author, Dr. Jeffrey Glick, toldThe Washington Postthat there are no specific studies that can confirm whether the drugs are associated with heartburn.
"It's very likely that the drugs have been used for several years and it's important that they are used for the shortest time in order to provide the best possible outcome for the patient and the patient's overall health," he said.
Other studies have found that patients taking Nexium and Prilosec have a slightly higher risk of having a heartburn than those taking a placebo. In that study, about one in every 10 people taking the drugs suffered a heartburn.
The other studies have also found that patients taking Nexium and Prilosec had a slightly higher chance of getting heartburn than those taking a placebo, and that was about one in every 10 people taking the drugs.
The drug's side effects include stomach upset, bloating, indigestion, gas and stomach pain. The drugs also may cause people to lose weight.
Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
This week's by mail can be access denied through this link:General Product DescriptionNexium 24HR Once Daily Dosing Tablets provide lasting relief from frequent heartburn and acid reflux. They providelasting symptomatic relief of frequent heartburn, acid regurgitation and other symptoms associated with gastro-oesophageal reflux.
Key Features
Directions For UseAdults 18 years of age and over:Take 1 tablet daily for at least 7 days and up to 14 days. Swallow the tablet whole with water, with or without food. Do not crush or chew the tablet. Do not take for more than 14 days unless drected byt a doctor.Not intended for immediate relief. It may take a few days to achieve maximum results.
WarningsAlways read and follow the directions before use. If symptoms persist, disconinue use and consult your healthcare professional. Keep out of reach of children. Do not use if you are pregnant or breast feeding, or under the age of 18.
IngredientsEach tablet contains: Esomeprazole 20mg (as Magnesium Trihydrate).
criptionsLose a achy chest, dizziness or acid reflux. Stand up and take the first dose that says “use only when needed. Do not use if you are dizzy or tired”.
DirectionsAdults 18 years of age and over: Take 1 tablet daily for at least 7 days and up to 14 days. Do not drink alcohol after taking this medicine
Other InformationThis product is to be used by: Adults over 18 years of age. Children under 18 years of age. Keep to the following doses: 10, 20, 40, 80, 100, 150,albeit on an as-needed basis:
Do not use if you are dizzy or tired"
If you are allergic to esomeprazole or any other ingredients of the product, do not use: -For external use only. -Do not use in pregnancy or if you are pregnant or breast feeding. -Do not use during the last 6 months of pregnancy. -Do not use on children below 18 years. -Do not use on pregnant women or breastfeeding women.
Each tablet contains: Sildenafil 100 mg. Esomeprazole is the active ingredient which gives this product its name is not known.
This product contains the active ingredient contains magnesium stearate.
If symptoms persist, tell your doctor.
CAUTIONDo not use in eyes. Do not use in eyes after the expiry date printed on the pack. Do not use if the cap has expired. Do not use if the pack is broken or if the bottle has expired. Do not use if the cap is dry. Do not use if the seal is broken. Do not use if the expiry date has not been applied. Do not use if the cap is eyes. Do not use if the package has the lot numbers shown on the lot to be on a regular computer. Do not use if the expiry date has passed. Do not use if the product is not in sight of user. Do not use if the package is young children may get the product.
medicineSUNLIFE #1 online medicine for CANCER BENGTH Supharch monograph is part of the healthcare informationizarrely promoted as to possibly cure high cholesterol and other related ailments. We strongly recommend you do not buy this product from us. Please read the fine print and careful language carefully. Please read the design and careful language carefully. We hope you have been well. Please do not buy from us and if you have any questions about this medicine, please contact us.
Nexium (Nexium 24 Hour) is a medicine containing the active ingredient esomeprazole. It is a proton pump inhibitor (PPI) which works to block the production of acid in the stomach. This aids in maintaining a healthy stomach and helps to relieve discomfort caused by acid reflux. It’s important to note that Nexium 24 Hour should only be taken under the guidance of a healthcare professional, as it is not effective against acid reflux.
Q1: How long does Nexium (Nexium 24 Hour) last?A: Nexium 24 Hour is generally required for healing of damaged and ulcerated esophagus. It helps to relieve symptoms such as heartburn, acid reflux, stomach pain and discomfort. The effect can last for up to 4 hours. The medication should be taken orally once a day, or at the same time daily. If you need to take Nexium 24 Hour for more than 4 days, your doctor will likely advise you to continue taking it as prescribed.
Q2: Can I take Nexium 24 Hour for acid reflux?A: Nexium 24 Hour is not suitable for use if you have heartburn or acid reflux. Nexium 24 Hour should only be used if the heartburn is accompanied by acid reflux disease (AHRD). It can also lead to a worsening of the condition. If you experience persistent or recurrent symptoms, please consult your doctor.
Q3: Do Nexium 24 Hour work?A: Nexium 24 Hour may not be effective against acid reflux but can be helpful for individuals who have acid reflux or heartburn.
Q4: Are there any side effects with Nexium 24 Hour?A: No, Nexium 24 Hour is not suitable for use by children and adolescents. There is no risk to the patient and no data is available on the safety and efficacy of Nexium 24 Hour. It should be used with caution in patients with certain medical conditions.
Q5: Can I take Nexium 24 Hour while breastfeeding?A: No, Nexium 24 Hour is not recommended for use while breastfeeding.
Q6: What if I forget to take Nexium 24 Hour?A: Take your missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the usual time. Do not take 2 doses at the same time.
Nexium, NEXIUM24HR [package insert]. New York, NY: Allergan, Inc; 2010.
https://www.nx.com/nx-d/nx-d_medicines_release/index.php?option=onomypharmacy# BeiLabs [Internet]. 2011. Accessed 11:26:28. doi:10.1093/brain/pwj/i275927https://www.bic.com/NEXIUM24HR/NEXIUM24HR.pdf [Internet]. New York, NY: Allergan Inc; 2010.https://www.nx.com/nx-d/nx-d_medicines_release/index.php?p=bb/p3c9a3e-49e-achi:26:28.https://www.drugsatfrance.com/nx-nx-nx-24-hour-effects-drug.html [Internet].https://www.drugsatfrance.com/nx-nx-nx-24-effects-drug.html [Internet].https://www.drugsatfrance.
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